Process Development Associate

Poseida Therapeutics, Inc. is seeking an outstanding candidate to join our Cell Therapy Development group at our La Jolla, San Diego, CA location. The Development Associate will be a key member of a dynamic team that develops and implements characterization strategies to support and enable process and clinical development of gene-engineered cell products. This is a lab-based position that will involve hands-on development of clinical manufacturing processes for selecting, gene-modifying and growing T cell subsets. This position will interface with our Research and Development team as well as with outside Contract Manufacturing Organizations. The ideal candidate will be skilled in T cell culture techniques, flow cytometry and have experience working in or supporting cGMP manufacturing projects. The candidate will have good oral and written communication skills, and will work with minimal supervision to design experiments, manage projects, collect data, and prepare reports.

Poseida Therapeutics is translating best-in-class gene engineering technologies into lifesaving cell therapies. The company is developing CAR T-cell immunotherapies for multiple myeloma, prostate and other cancer types, as well as gene therapies for orphan diseases. P-BCMA-101 is Poseida’s lead CAR-T therapy currently in Phase 1 clinical development for the treatment of multiple myeloma. Poseida has assembled a suite of industry-leading gene engineering technologies, including the piggyBac™ DNA Modification System, TAL-CLOVER™ and Cas-CLOVER™ site-specific nucleases, and Footprint-Free™ Gene Editing (FFGE). For more information, visit

Required Experience and Skills:

– MS with ≥ 1 years of experience in the field of immunology, molecular biology, or related field
– Bachelors in life sciences with 3-5 years of relevant experience
– Excellent aseptic technique. Proficient in cell culture of human lines and primary cells
– Experience in biologicals process development or cGMP clinical manufacturing
– Excellent communication skills, data presentation and interpersonal skills
– Basic computer skills in Excel, PowerPoint, and word processing
– Attention to detail, initiative, and strong organizational skills
– Able to travel up to 20%

Preferred Experience and Skills:

– Experience in human T cell biology with demonstrated proficiency in a broad range of cellular immunology techniques, including flow cytometry and in vitro T cell functional assays (cytotoxicity, ELISA, proliferation, Luminex)
– Served as Person-in-Plant for cGMP manufacturing of critical raw materials or biological products
– Experience with industry cell separation technologies (magnetic beads, centrifugation-based techniques, etc.) and FACS sorting
– Culture, expansion, and manipulation of T cells. Experience with stem cells is a plus
– Experience with drafting SOP and batch record writing. Manufacturing experience is a plus
– Experience with Design of Experiment, JMP, and FlowJo