Director, Immuno-Oncology

Poseida Therapeutics, Inc. is seeking an outstanding candidate to direct our Immuno-Oncology team in La Jolla, San Diego, CA. The Director will lead, manage, and develop the Immuno-Oncology group with a focus on rapid advancement of CAR-T products into Phase I clinical trials. The successful candidate will possess a Ph.D. or equivalent, demonstrate excellent oral and written communication skills, have at least 6 years of relevant experience as well as a proven track record in the areas of T cell biology, immunology, molecular biology, tumor immunology, flow cytometry and CAR-T development. Primarily, the role will:

  • Oversee and direct a team of highly creative and innovative scientists in the development of immuno-oncology related products, especially CAR-Ts
  • Act as a liaison with all essential internal functional groups and external collaborators, consultants, CMOs, and/or specialists
  • Keep current on trends, new products, and technologies in CAR-T development
  • Serve as a subject matter expert related to CAR-T and gene therapy-related technologies and strategies
  • Manage Immuno-Oncology group to achieve project and organizational objectives via individualized goal-setting, oversight, feedback, technical direction, and coaching
  • Work with senior management to ensure goals are aligned with our strategic direction and contribute to the development of long term research and pre-clinical immuno-oncology strategy
  • Develop talent by providing professional and personal growth opportunities and mentorship
  • Effectively manage Immuno-Oncology resources (e.g. budget, capital, headcount, allocations, etc.)
  • Organize, communicate, and present complex data sets to senior management and key stakeholders

Poseida Therapeutics is translating best-in-class gene engineering technologies into lifesaving cell therapies. The company is developing CAR T-cell immunotherapies for multiple myeloma, prostate and other cancer types, as well as gene therapies for orphan diseases. P-BCMA-101 is Poseida’s lead CAR-T therapy currently in Phase 1 clinical development for the treatment of multiple myeloma. Poseida has assembled a suite of industry-leading gene engineering technologies, including the piggyBac™ DNA Modification System, TAL-CLOVER™ and Cas-CLOVER™ site-specific nucleases, and Footprint-Free™ Gene Editing (FFGE). For more information, visit

Required Experience and Skills:

  • Ph.D. or equivalent in immunology, molecular biology, or related field and ≥ 6 years of relevant experience in the field
  • A detailed knowledge, publication record, and proven experience in the areas of cellular immunology, tumor immunology, molecular biology, and CAR-T development
  • Expertise in the characterization, culture, expansion, and manipulation of T cells as it pertains to the development, testing, and application of CARs in vitro and in vivo
  • Demonstrated track record of effective management and leadership skills
  • Excellent written and verbal communications skills, and the ability to present and defend positions and approaches critical to program progression and success
  • Logical in thought and detail-focused
  • Highly motivated team player and strong leader willing to contribute to a growing biotech organization

Preferred Experience and Skills:

  • Genetic manipulation using CRISPRs, TALENs, or ZFNs
  • Electroporation techniques and technologies (Plasmid DNA, IVT RNA)
  • Viral vector design and transduction techniques (retroviral, lentiviral)
  • Work with external academic, biotechnology, and contract research organizations